Bioavailable Support for Energy, Muscle, Nerve, Bone, and Stress Resilience*
What It Does
Magnesium Citrate delivers a highly bioavailable form of magnesium, a mineral essential for mitochondrial energy production, neuromuscular function, cardiovascular health, bone density, and stress response regulation.* This dual-action formula supplies both magnesium and citrate which are key participants in the citric acid cycle to support cellular metabolism and resilience in high-demand tissues such as the brain, heart, and muscles.*
How It Works
• Mitochondrial Energy Production: Magnesium is required for the stability and activation of ATP (as Mg-ATP), and citrate is a central intermediate in the citric acid cycle that generates cellular energy.*[1,2]
• Muscle and Nerve Function: Magnesium regulates muscle contraction and nerve signaling, including in the heart and vasculature.* Deficiency may impair these functions, especially under physical or metabolic stress.*[3]
• Bone Health: Magnesium is essential for calcium absorption, vitamin D activation, and bone matrix formation.* Higher magnesium intake is linked to greater bone mineral density in observational and interventional studies.*[4]
• Stress Regulation and Mood: Magnesium contributes to neurotransmitter metabolism and modulates catecholamines via COMT, as well as adrenal cortisol output.* Magnesium supports mood, relaxation, and sleep quality under stress.*[5,6,7]
• Population Need: Magnesium intake is suboptimal in most U.S. adults, especially women, due to depleted soil levels and food processing losses.* Magnesium citrate is more bioavailable and better tolerated than magnesium oxide or sulfate forms.*[2]
Who It’s For
Magnesium Citrate is recommended for individuals experiencing occasional muscle tension or have goals involving energy status, bone health, optimal sleep or stress resilience.* It may be especially beneficial for active individuals, those with high cognitive or emotional demands, or those with potential dietary insufficiency.*
Special Features
This formula combines elemental magnesium with citrate to target both energy and pH balance. It is well-absorbed, gentle on the GI tract for most individuals, and free from major allergens.*
References
1. Lindberg JS, et al. J Am Coll Nutr. 1990;9(1):48-55.
2. DiNicolantonio JJ, et al. Open Heart. 2018;5(1):e000668. doi:10.1136/openhrt-2017-000668
3. Yamanaka R, et al. Sci Rep. 2016;6:30027. doi:10.1038/srep30027
4. Groenendijk I, et al. Bone. 2022;154:116233. doi:10.1016/j.bone.2021.116233
5. Shimosawa T, et al. Hypertension. 2004;44(6):897-902.
6. Schutten JC, et al. Clin Endocrinol (Oxf). 2021;94(2):150-7.
7. Rawji A, et al. Cureus. 2024;16(4):e59317. doi:10.7759/cureus.59317
