Allergy Research Group TMG - 100 vegetarian capsules bottle front label

TMG - supplement fact label with Trimethylglycine

TMG - suggested use: 1 capsule twice daily before meals

TMG - key benefits including Homocysteine metabolism support

TMG Trimethylglycine capsule size graphic highlighting concentrated methylation support and 0.96 inch capsule size

TMG Trimethylglycine ingredient spotlight graphic explaining complementary methylation support alongside B vitamin supplements

SKU 73230

TMG

Name: TMG
Brand: Allergy Research Group
SKU: 73230
Price: 26.29 USD
Availability: InStock

Supports Methylation*

Trimethylglycine (TMG) supports methylation, liver health, and homocysteine metabolism while acting as a cellular osmolyte for stress resilience.* TMG assists homocysteine to be metabolized into methionine, resulting in the production of DMG (dimethylglycine).* The two major functions of TMG in humans are as an osmolyte to protect cells under stress and as a methyl-group donor.*

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Ingredients

Serving Size: 1 capsule
Servings Per Container: 100

Amount per Serving:

Trimethylglycine: 750 mg

Other Ingredients

Hydroxypropyl methylcellulose, rice concentrate, silicon dioxide.

Suggested Use

As a dietary supplement, take 1 capsule twice daily before meals, or as directed by a healthcare practitioner.

If you are pregnant or lactating, have any health condition or are taking any medication, consult your healthcare practitioner before use.

Store in a cool, dry place, tightly capped, away from light. Keep out of the reach of children. Use only if safety seal is intact. Variations in product color may occur.

TMG

$26.29

What It Does

Trimethylglycine (TMG), also known as betaine, supports normal homocysteine metabolism and helps maintain healthy methylation pathways. It contributes to liver and kidney cellular health while promoting osmotic balance and protecting cellular structures under stress.*

How It Works

• Trimethylglycine (TMG): provides methyl groups to convert homocysteine to methionine via the enzyme betaine homocysteine methyltransferase (BHMT), especially active in the liver and kidneys.*[1]
• Bypasses MTHFR limitations: offering an alternative methylation route for individuals with the 677TT polymorphism or functional folate needs.*[2]
• Supports healthy homocysteine metabolism.*[3-4]
• Effective at lower doses with benefits observed at lower dietary intake levels of betaine.*[5]
• Acts as a cellular osmolyte protecting proteins, enzymes, and DNA while improving cellular fluid retention and resilience to osmotic stress which is particularly supportive for kidney cells.*[6][2]

Who It's For

Ideal for individuals seeking to support cardiovascular and liver health, methylation balance, or homocysteine support, especially those with genetic polymorphisms affecting folate metabolism.*

Special Features

Offers dual-action support for methylation and cellular osmoprotection, making it uniquely valuable for stress-prone tissues like the liver and kidneys.*

References

1. Obeid R. Nutrients. 2013;5(9):3481–95.
2. Arumugam MK et al. Biology. 2021;10(6):456. doi:10.3390/biology10060456
3. Steenge GR et al. J Nutr. 2003;133(5):1291–5.
4. McRae MP. J Chiropr Med. 2013;12(1):20–5.
5. Olthof MR et al. J Nutr. 2003;133(12):4135–8.
6. Craig S. Am J Clin Nutr. 2004;80(3):539–49

Additional Information

Supports Healthy Methylation and Cellular Resilience*

TMG

Supports Methylation*

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What It Does

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